Construction began in early 2022, and Durango opened on December 5, 2023. In 2021, Station's parent company, Red Rock Resorts, announced plans to proceed with the project once again. However, before the start of construction, the project was delayed indefinitely due to the Great Recession.

The company later announced plans to begin building a scaled-down version of Durango Station in 2009, with an opening in 2011. The project was approved by the Clark County Commission despite the opposition, although Station did not plan to begin construction for several years.

The 1,000-room project was met with opposition from area residents, who disagreed with its size and its proposed location near a new elementary school. Four years later, the company announced plans for a hotel-casino, known then as Durango Station. Station Casinos purchased the property from developer Jim Rhodes in 2000. The resort includes an 83,178 sq ft (7,727.5 m 2) casino, 209 rooms in a 15-story tower, and several restaurants. It is located along Durango Drive, beside the Las Vegas Beltway.

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